Detection of TREM‑2 in RAW 264.7 Mouse Cell Line by Flow Cytometry.
RAW 264.7 mouse monocyte/macrophage cell line was stained with Rat Anti-Human/Mouse TREM‑2 Alexa Fluor® 750‑conjugated Monoclonal Antibody (Catalog # FAB17291S, filled histogram) or isotype control antibody (Catalog # IC013S, open histogram). View our protocol for Staining Membrane-associated Proteins.
Detection of TREM‑2 in Human PBMCs by Flow Cytometry.
Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human Integrin alpha M/CD11b PE‑conjugated Monoclonal Antibody (Catalog # FAB16991P) and either (A) Rat Anti-Human/Mouse TREM‑2 Alexa Fluor® 750‑conjugated Monoclonal Antibody (Catalog # FAB17291S) or (B) Rat IgG2B Alexa Fluor 750 Isotype Control (Catalog # IC013S). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
TREM-2 is a single V-type Ig-like domain-containing transmembrane (TM) receptor that is expressed on cells of the hematopoietic and nervous systems. Although single residue polymorphisms may exist, one soluble isoform variant is reported that shows an 88 amino acid (aa) substitution for the C-terminal 66 aa of the TM isoform. TREM-2 is best known for its association with the adapter protein DAP12 that delivers an activating signal that plays a role in both the innate and adaptive immune responses.
Triggering Receptor Expressed on Myeloid Cells 2
Entrez Gene IDs:
TREM2; TREM-2; Trem2a; Trem2b; Trem2c; TREM-2triggering receptor expressed on myeloid cells 2a; Triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2
Have you used Human/Mouse TREM-2 Alexa Fluor® 750-conjugated Antibody?
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