Human Myelin PLP (NP_000524.3) VersaClone cDNA

Name: Human Myelin PLP (NP_000524.3) VersaClone cDNA
Brand: R&D Systems
SKU: RDC3643
Price: 270 USD
Availability: InStock

R&D Systems | Catalog # RDC3643

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Product Documents

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Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_000524.3

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Myelin PLP

Human PLP (also known as lipophilin) is a 30 kDa protein (277 amino acids) found in myelin of the CNS and PNS. Expressed by oligodendrocytes and Schwann cells, PLP stabilizes myelin by preventing lipid bilayer fusion, and aids in compaction. Different mutations of the human PLP gene product result in two neurological disorders - Pelizaeus-Merzbacher disease and Spastic Paraplegia type 2.

Long Name

Proteolipid Protein

Alternate Names

DM-20, Lipophilin, MMPL, PLP1, SPG2

Entrez Gene IDs

5354 (Human); 18823 (Mouse)

Gene Symbol

PLP1

UniProt

NP_000524.3 (Human)

Additional Myelin PLP Products

Product Documents for Human Myelin PLP (NP_000524.3) VersaClone cDNA

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Certificate of Analysis

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Product Specific Notices for Human Myelin PLP (NP_000524.3) VersaClone cDNA

For research use only

Related Research Areas

Glial Lineage Markers

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