Human Neuregulin-2/NRG2 (NP_004874.1) VersaClone cDNA

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Human Neuregulin-2/NRG2 (NP_004874.1) VersaClone cDNA
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Human Neuregulin-2/NRG2 (NP_004874.1) VersaClone cDNA Summary


Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: Neuregulin-2/NRG2

The neuregulin (also known as heregulin) cytokine family is comprised of four genes that encode a large number of secreted or membrane-bound isoforms. All family members share an EGF-like domain that interacts with the ErbB family of tyrosine kinase receptors. The NRG1 gene is the most pleiotropic, encoding more than 14 soluble or transmembrane proteins. NRG1 isoforms can be classified into type I (neu differentiation factor, NDF; heregulin, HRG; acetylcholine receptor inducing activity, ARIA), type II (glial growth factor, GGF) and type III (sensory and motor neuron-derived factor, SMDF) isoforms. NRG proteins show distinct spatial and temporal expression patterns and play important roles during development of both the nervous system and the heart.

Entrez Gene IDs
9542 (Human); 100042150 (Mouse); 432361 (Rat)
Alternate Names
divergent of neuregulin-1; DON1; Don-1; HRG2; neuregulin 2; Neuregulin2; Neuregulin-2; NRG2; NTAK; NTAKneural- and thymus-derived activator for ErbB kinases; pro-neuregulin-2, membrane-bound isoform; pro-NRG2


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