Human OCIL/CLEC2d (NP_037401) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Product Details

Human OCIL/CLEC2d (NP_037401) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: OCIL/CLEC2d

OCIL/CLEC2D, also known as lectin-like transcript-1 (LLT-1), is a type II transmembrane protein belonging to the natural killer cell receptor group of the C-type lectin superfamily. It is found on hematopoietic cells, osteoblasts, and chondrocytes. Human OCIL preferentially binds high molecular weight sulfated glycosaminoglycans and is a ligand for the single human NKR-P1A receptor (CD161). Human OCIL blocks osteoclast differentiation. Engagement of OCIL with CD161 on NK cells also inhibits NK cell-mediated cytotoxicity and IFN-gamma secretion.

Long Name
Osteoclast Inhibitory Lectin
Entrez Gene IDs
29121 (Human); 93694 (Mouse)
Alternate Names
CLAXLLT-1; CLEC2D; C-type lectin domain family 2 member D; C-type lectin domain family 2, member D; C-type lectin related f; Lectin-like NK cell receptor; Lectin-like transcript 1; LLT1; LLT1Osteoclast inhibitory lectin; OCIL; OCILmember D


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