Human p53R2 (NP_056528.2) VersaClone cDNA

Name: Human p53R2 (NP_056528.2) VersaClone cDNA
Brand: R&D Systems
SKU: RDC3566
Price: 250 USD
Availability: InStock

R&D Systems | Catalog # RDC3566

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Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_056528.2

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: p53R2

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and g-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumour suppression.

Alternate Names

RRM2B

Entrez Gene IDs

50484 (Human); 382985 (Mouse)

Gene Symbol

RRM2B

UniProt

NP_056528.2 (Human)

Additional p53R2 Products

Product Documents for Human p53R2 (NP_056528.2) VersaClone cDNA

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Certificate of Analysis

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Product Specific Notices for Human p53R2 (NP_056528.2) VersaClone cDNA

For research use only

Related Research Areas

p53 Pathway

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