Human PANK2 (NP_705902.2) VersaClone cDNA

Name: Human PANK2 (NP_705902.2) VersaClone cDNA
Brand: R&D Systems
SKU: RDC3782
Price: 270 USD
Availability: InStock

R&D Systems | Catalog # RDC3782

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Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_705902.2

Background: PANK2

PANK2 encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms.

Long Name

Pantothenate Kinase 2

Alternate Names

FLJ11729, HPANK2, NBIA1, PKAN

Entrez Gene IDs

80025 (Human); 74450 (Mouse)

Gene Symbol

PANK2

UniProt

NP_705902.2

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Product Documents for Human PANK2 (NP_705902.2) VersaClone cDNA

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Product Specific Notices for Human PANK2 (NP_705902.2) VersaClone cDNA

For research use only

Related Research Areas

Bcl-2 Proteins and Regulators

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