Human Peptidase Inhibitor 16/PI16 Alexa Fluor® 594-conjugated Antibody

Catalog #: AF4980T Datasheet / COA / SDS

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AF4980T-100UG

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All Peptidase Inhibitor 16/PI16 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Peptidase Inhibitor 16/PI16 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human Peptidase Inhibitor 16/PI16 in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Peptidase Inhibitor 16/PI16
Leu28-Leu437
Accession # AAH35634

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Peptidase Inhibitor 16/PI16

PI16 (Peptidase Inhibitor 16; also PSP94-binding protein) is a 70‑75 kDa member of the CRISP family of proteins. It is expressed by prostatic fibroblasts and cardiomyocytes and is known to bind PSP94. The human PI16 precursor is 463 amino acids (aa) in length. It contains a 27 aa signal peptide plus a 436 aa mature region. The mature region has been described as being either a type I transmembrane (TM) glycoprotein with a TM segment between aa 443‑462, or a GPI‑linked glycoprotein with C‑terminal cleavage between Lys437‑Asn438. Three potential variants exist. One shows a deletion of aa 231‑423, a second shows a 9 aa substitution for the C‑terminal 64 aa and a third shows a 43 aa insertion after Cys197. Over aa 28‑437, human PI16 is 67% aa identical to mouse PI16.

Entrez Gene IDs

221476 (Human); 74116 (Mouse); 294312 (Rat)

Alternate Names

CRISP9; CRISP-9; Cysteine-rich secretory protein 9; dJ90K10.5; DKFZp586B1817; MGC45378; microseminoprotein, beta-binding protein; MSMBBP; Peptidase Inhibitor 16; PI16; PI-16; protease inhibitor 16; PSP94-binding protein; PSPBP