Human Plexin A3 (NP_059984) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Human Plexin A3 (NP_059984) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: Plexin A3

Plexin A3 (also known as SEX) is a 220 kDa member of the Plexin A subfamily of semaphorin receptors. Plexin A3 interacts with neuropilins 1 and 2 and binds class 3 semaphorins.

Mature mouse Plexin A3 is predicted to be an 1853 amino acid (aa) type I transmembrane glycoprotein that contains a 1202 aa extracellular domain (ECD) and a 629 aa cytoplasmic region. The ECD contains one semaphorin domain (aa 34 - 473), three plexin-semaphorin-integrin (PSI) domains (aa 492 - 830) and four lg-like plexin-transcription factor (IPT) repeats (aa 841 - 1209). Over aa 35 - 150, mouse Plexin A3 is 99% and 97% aa identical to rat and human Plexin A3, respectively.

Entrez Gene IDs
55558 (Human); 18846 (Mouse); 309280 (Rat)
Alternate Names
HSSEXGENE; Plexin A3; plexin-4; plexin-A3; Plxn3; PLXN4; PLXNA3; Semaphorin receptor SEX; Sex chromosome X transmembrane protein of HGF receptor family 3; SEX; SEXPLEXIN-A3,6.3; XAP-6


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