PLK1 is a member of the Polo-Like Kinase family that localizes to centrosomes or spindle pole bodies and undergoes dramatic subcellular relocation during the cell cycle. Deregulated activities of PLKs often result in abnormalities in centrosome duplication, maturation, and/or microtubule dynamics. PLKs also regulate the function of the Golgi complex. Deregulated expression of human PLK1 is strongly correlated with the development of many types of malignancies, and ectopic expression of PLK1 dominant negative protein leads to rapid cell death.
Human PLK1 (NP_005021.2) VersaClone cDNA
R&D Systems | Catalog # RDC3216
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: PLK1
Long Name
Polo-like Kinase 1
Alternate Names
STPK13
Gene Symbol
PLK1
UniProt
Additional PLK1 Products
Product Documents for Human PLK1 (NP_005021.2) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human PLK1 (NP_005021.2) VersaClone cDNA
For research use only
Related Research Areas
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