Human Prominin 2 Alexa Fluor® 594-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB2024T-100UG
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Human Prominin 2 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human Prominin 2. Stains human Prominin 2-transfected cells but not irrelevant transfectants.
Source
Monoclonal Mouse IgG2b Clone # 244029
Immunogen
NS0 mouse myeloma cell line transfected with human Prominin 2
Ala27-Leu834
Accession # AAM10541
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 594

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
LNCaP human prostate cancer cell line

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Prominin 2

Prominin 2 is a pentaspan membrane glycoprotein predominantly expressed in neuroepithelial cells, hematopoietic stem cells and epithelial cells of the adult kidney and digestive tract (1, 2). Prominin 2 is a 112-kDa glycoprotein structurally related to prominin 1 (CD133). The amino acid identity between prominin 1 and prominin 2 is low (<30%), but they exhibit some redundant functions.

References
  1. Fargeas, C.A. et al. (2003) J. Biol. Chem. 278(10):8586.
  2. Fargeas, C.A. et al. (2003) Stem Cells 21(4):506.
Entrez Gene IDs
150696 (Human); 192212 (Mouse); 192211 (Rat)
Alternate Names
hPROML2; MGC138714; PROM2; PROM-2; Prominin 2; prominin-2; Prominin-like protein 2; prominin-related protein; PROML2

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