Detection of Protocadherin-19 in SH‑SY5Y Human Cell Line by Flow Cytometry.
SH‑SY5Y human neuroblastoma cell line was stained with Mouse Anti-Human Protocadherin-19 APC‑conjugated Monoclonal Antibody (Catalog # FAB8626A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
Protocadherin 19 (PCDH19) is a member of the d2 subfamily of the non-(gene) clustered group of the PDCH (Protocadherin) family that belongs to the Cadherin superfamily of molecules. d2 subfamily members are characterized by both the absence of a Protein Phosphatase-1 alpha binding domain, and the presence of the two short amino acid motifs in their cytoplasmic domains. PDCH19 is found in the basal ganglia and hippocampus, and will undergo weak homophilic interaction. PDCH19 mutations have been associated with epilepsy and mental retardation.
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