Human Protocadherin-19 APC‑conjugated Antibody

R&D Systems | Catalog # FAB8626A

R&D Systems
Discontinued Product
FAB8626A has been discontinued. View all Protocadherin-19 products.

Key Product Details

Species Reactivity

Human

Applications

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 921614
View all Protocadherin-19 Primary Antibodies »

Product Specifications

Immunogen

HEK293 human embryonic kidney cell line transfected with human Protocadherin-19
Met1-Ser678
Accession # Q8TAB3

Specificity

Detects human Protocadherin-19 in direct ELISA and flow cytometry.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Human Protocadherin-19 APC‑conjugated Antibody

Detection of Protocadherin-19 antibody in SH-SY5Y Human Cell Line antibody by Flow Cytometry.

Detection of Protocadherin-19 in SH‑SY5Y Human Cell Line by Flow Cytometry.

SH-SY5Y human neuroblastoma cell line was stained with Mouse Anti-Human Protocadherin-19 APC-conjugated Monoclonal Antibody (Catalog # FAB8626A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Detection of Protocadherin-19 in Jurkat Human Cell Line by Flow Cytometry.

Jurkat human T cell leukemia cells were stained with Mouse Anti-Human Protocadherin-19 APC-conjugated Monoclonal Antibody (Catalog # FAB8626A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human Protocadherin-19 APC‑conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: SH‑SY5Y human neuroblastoma cell line and Jurkat human acute T cell leukemia cell line

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Flow Cytometry

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: Protocadherin-19

Protocadherin 19 (PCDH19) is a member of the d2 subfamily of the non-(gene) clustered group of the PDCH (Protocadherin) family that belongs to the Cadherin superfamily of molecules. d2 subfamily members are characterized by both the absence of a Protein Phosphatase-1 alpha binding domain, and the presence of the two short amino acid motifs in their cytoplasmic domains. PDCH19 is found in the basal ganglia and hippocampus, and will undergo weak homophilic interaction. PDCH19 mutations have been associated with epilepsy and mental retardation. 

Alternate Names

EFMR, EIEE9, PCDH19, Protocadherin19

Entrez Gene IDs

57526 (Human); 279653 (Mouse)

Gene Symbol

PCDH19

UniProt

Q8TAB3

Additional Protocadherin-19 Products

Product Documents for Human Protocadherin-19 APC‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human Protocadherin-19 APC‑conjugated Antibody

For research use only

Related Research Areas

Cadherin Superfamily

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