Protogenin (Early/proto in expression, neogenin-like; also Prtg) is a 130 kDa (predicted), type I transmembrane member of the DCC/Neogenin family of proteins. It is expressed in mouse presomitic mesoderm, paraxial mesoderm, and neural tube. Mature mouse protogenin is 1168 amino acids (aa) in length. It contains a 920 aa extracellular domain (ECD) (aa 24 - 943) plus a 224 aa cytoplasmic region. The ECD contains four consecutive Ig-like domains (aa 24 - 405), followed by five sequential fibronectin type III domains (aa 413 - 908). The ECD of mouse protogenin shares 98%, 87% and 93% aa identity with the ECD of rat, chick and human protogenin, respectively.
Human Protogenin (NP_776175) VersaClone cDNA
R&D Systems | Catalog # RDC1953
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Protogenin
Alternate Names
IGDCC5, PRTG, RPTG, Shen-Dan
Gene Symbol
PRTG
UniProt
Additional Protogenin Products
Product Documents for Human Protogenin (NP_776175) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human Protogenin (NP_776175) VersaClone cDNA
For research use only
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