Human PTP alpha/PTPRA (NP_543030) VersaClone cDNA

R&D Systems | Catalog # RDC1049

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Key Product Details

Species

Human

Accession Number

NP_543030

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: PTP alpha/PTPRA

PTP alpha is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.

Long Name

Protein Tyrosine Phosphatase Receptor-type alpha

Alternate Names

HEPTP, HLPR, LRP, PTPase-alpha, PTPRA, PTPRL2

Entrez Gene IDs

5786 (Human); 19262 (Mouse); 25167 (Rat)

Gene Symbol

PTPRA

UniProt

NP_543030

Additional PTP alpha/PTPRA Products

Product Documents for Human PTP alpha/PTPRA (NP_543030) VersaClone cDNA

Certificate of Analysis

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Product Specific Notices for Human PTP alpha/PTPRA (NP_543030) VersaClone cDNA

For research use only

Related Research Areas

Epigenetics
Phosphatases and Regulators

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