Human PTP alpha/PTPRA (NP_543030) VersaClone cDNA

Name: Human PTP alpha/PTPRA (NP_543030) VersaClone cDNA
Brand: R&D Systems
SKU: RDC1049
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC1049

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Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_543030

Background: PTP alpha/PTPRA

PTP alpha is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.

Long Name

Protein Tyrosine Phosphatase Receptor-type alpha

Alternate Names

HEPTP, HLPR, LRP, PTPase-alpha, PTPRA, PTPRL2

Entrez Gene IDs

5786 (Human); 19262 (Mouse); 25167 (Rat)

Gene Symbol

PTPRA

UniProt

NP_543030

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Product Specific Notices for Human PTP alpha/PTPRA (NP_543030) VersaClone cDNA

For research use only

Related Research Areas

Epigenetics

Phosphatases and Regulators

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