Protein Tyrosine Phosphatase, Receptor-type T (PTPRT), also known as RPTPrho, dephosphorylates tyrosine residues in proteins. PTPRT is present in many tissues, including brain, heart, lung, and colon. Genetic screening of colon cancers indicates that the PTPRT gene has a high incidence of missense mutations that reduce phosphatase activity in the encoded protein. Overexpression of intact PTPRT in cancer cell lines inhibits cell proliferation, suggesting that the phosphatase is a tumor suppressor.
Human PTP rho/PTPRT (NP_573400) VersaClone cDNA
R&D Systems | Catalog # RDC2265
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: PTP rho/PTPRT
Long Name
Protein Tyrosine Phosphatase Receptor-type T
Alternate Names
PTPRT, RPTP-rho
Gene Symbol
PTPRT
UniProt
Additional PTP rho/PTPRT Products
Product Documents for Human PTP rho/PTPRT (NP_573400) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human PTP rho/PTPRT (NP_573400) VersaClone cDNA
For research use only
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