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Human PTP sigma /PTPRS Alexa Fluor® 750-conjugated Antibody

Catalog #: AF3430S Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF3430S-100UG
Product Details
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human PTP sigma /PTPRS Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects the endogenous cleaved extracellular domain of human PTP sigma /PTPRS in Western blots. In Western blots, less than 1% cross-reactivity with recombinant human LAR, PTPR beta, PTPRδ, PTPRµ, or PTPR kappa is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human PTPσ/PTPRS
Glu30-Gly1260
Accession # NP_570924
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: PTP sigma/PTPRS

Protein Tyrosine Phoshatase Receptor-type sigma (PTPR sigma ), also known as PTP sigma, is an integral membrane protein with a non-glycosylated molecular weight of 214 kilodaltons. The extracellular domain, which was used as immunogen, is cleaved near the cell membrane by an endoprotease to generate a glycated 140 kDa protein. Significant levels of this protein are found in the brain and in endocrine tissues such as the pituitary gland and pancreas. Knockout mice deficient in PTPR sigma have severe neurological deficits and most die shortly after birth.

Long Name
Protein Tyrosine Phosphatase Receptor-type Sigma
Entrez Gene IDs
5802 (Human); 19280 (Mouse)
Alternate Names
EC 3.1.3.48; protein tyrosine phosphatase PTPsigma; protein tyrosine phosphatase, receptor type, S; protein tyrosine phosphatase, receptor type, sigma; PTP sigma; PTPR sigma; PTPRS; PTPSIGMA; receptor-type tyrosine-protein phosphatase S; Receptor-type tyrosine-protein phosphatase sigma; R-PTP-S; R-PTP-sigma

Product Datasheets

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