Human Pyruvate Carboxylase/PC (NP_071504.2) VersaClone cDNA

Name: Human Pyruvate Carboxylase/PC (NP_071504.2) VersaClone cDNA
Brand: R&D Systems
SKU: RDC3664
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC3664

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Product Documents

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Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species

Human

Accession Number

NP_071504.2

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: Pyruvate Carboxylase/PC

PCB encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq]

Long Name

Pyruvate Carboxylase

Alternate Names

PC, PCB

Entrez Gene IDs

5091 (Human)

Gene Symbol

UniProt

NP_071504.2

Additional Pyruvate Carboxylase/PC Products

Product Documents for Human Pyruvate Carboxylase/PC (NP_071504.2) VersaClone cDNA

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Certificate of Analysis

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Product Specific Notices for Human Pyruvate Carboxylase/PC (NP_071504.2) VersaClone cDNA

For research use only

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