Human Sirtuin 4/SIRT4 (NP_036372.1) VersaClone cDNA

R&D Systems | Catalog # RDC3411

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Key Product Details

Species

Human

Accession Number

NP_036372.1

Background: Sirtuin 4/SIRT4

SIRT4 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

Long Name

Silent Mating Type Information Regulation 4 Homolog

Alternate Names

SIR2L4, SIRT4

Entrez Gene IDs

23409 (Human); 75387 (Mouse)

Gene Symbol

SIRT4

UniProt

NP_036372.1 (Human)

Additional Sirtuin 4/SIRT4 Products

Product Documents for Human Sirtuin 4/SIRT4 (NP_036372.1) VersaClone cDNA

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Product Specific Notices for Human Sirtuin 4/SIRT4 (NP_036372.1) VersaClone cDNA

For research use only

Related Research Areas

Epigenetics
p53 Pathway

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