Human SLC6A4/5-HTTLPR (NP_001036) VersaClone cDNA

Name: Human SLC6A4/5-HTTLPR (NP_001036) VersaClone cDNA
Brand: R&D Systems
SKU: RDC1060
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC1060

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Background
Product Documents
Specific Notices

Key Product Details

Species

Human

Accession Number

NP_001036

Background: SLC6A4/5-HTTLPR

Serotonin transporter encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Long Name

Solute Carrier Family 6 Member 4

Alternate Names

5-HT Transporter, 5-HTT, 5-HTTLPR, 5HTTLPR, OCD1, Serotonin Transporter 1, SERT

Entrez Gene IDs

6532 (Human); 15567 (Mouse); 25553 (Rat)

Gene Symbol

SLC6A4

UniProt

NP_001036

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Product Specific Notices for Human SLC6A4/5-HTTLPR (NP_001036) VersaClone cDNA

For research use only

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