Human SorCS1 (NP_443150) VersaClone cDNA

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Human SorCS1 (NP_443150) VersaClone cDNA
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Human SorCS1 (NP_443150) VersaClone cDNA Summary


Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: SorCS1

SorCS proteins are members of the Vps10p (vacuolar protein-sorting 10 protein) family of sorting receptors. They are synthesized as proforms that undergo proteolytic processing to generate mature type I transmembrane receptors. The extracellular domains (ECD) show an imperfect LRR plus a Vps10p domain. The SorCS1 Vps10p domain binds both PDGF-BB and NGF-propeptide, while the SorCS3 Vps10p domain binds both pro- and mature NGF.

Long Name
Sortilin-related VPS10 Domain Containing Receptor 1
Entrez Gene IDs
114815 (Human); 58178 (Mouse); 309533 (Rat)
Alternate Names
FLJ41758; FLJ43475; FLJ44957; hSorCS; SORCS receptor 1; SORCS; SorCS1; sortilin-related VPS10 domain containing receptor 1; VPS10 domain receptor protein SORCS 1; VPS10 domain receptor SorCS; VPS10 domain-containing receptor SorCS1


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