SOX5 (SRY-related HMG box) is a 75‑80 kDa Group D member of the SOX family of DNA-binding proteins. It is expressed in fetal chondrocytes and skeletal muscle, with a short form appearing in spermatids. SOX5 form homodimers and heterodimerizes with SOX6. Human SOX5 is 763 amino acids (aa) in length and contains two coiled-coil regions (aa 193‑274 and 448‑515), plus one Q/glutamine (aa 234‑272) and one HMG box (aa 556‑624). HMG domains participate in DNA-binding and protein‑protein interaction. There are two alternate start sites at Met14 and Met417 (which creates a short/testis form), plus one variant with a three aa substitution for aa 389‑763, another variant with a two aa substitution for aa 1‑388, and a third variant with a one aa substitution for aa 534‑763. Over aa 417‑763, human SOX5 is 97% aa identical to mouse SOX5.
Human SOX5 Alexa Fluor™ Plus 647‑conjugated Antibody
R&D Systems | Catalog # AF5286AFP647
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Specifications
Specificity
Clonality
Host
Isotype
Applications for Human SOX5 Alexa Fluor™ Plus 647‑conjugated Antibody
Western Blot
Formulation, Preparation, and Storage
Formulation
Shipping
Stability & Storage
Background: SOX5
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Alternate Names
Gene Symbol
UniProt
Additional SOX5 Products
Product Documents for Human SOX5 Alexa Fluor™ Plus 647‑conjugated Antibody
Certificate of Analysis
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Product Specific Notices for Human SOX5 Alexa Fluor™ Plus 647‑conjugated Antibody
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
For research use only
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Protocols
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- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
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