Human STYK1 Alexa Fluor® 488-conjugated Antibody
Human STYK1 Alexa Fluor® 488-conjugated Antibody Summary
Asp72-Val320
Accession # Q6J9G0
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: STYK1
STYK1 (Ser/Thr/Tyr kinase 1; also NOK, or “novel oncogene with kinase-domain”) is a 50 kDa, distant member of the FGFR/PDGFR family of tyrosine kinases. It appears to be intracellular, even though it contains a putative transmembrane segment. Both MAPK and PI3K pathways are activated by STYK1 activity, and STYK1 is associated with oncogenesis. Human STYK1 is 422 amino acids (aa) in length. It contains 25 aa N-terminus, a 21 aa putative transmembrane segment, and a 396 aa C-terminus that contains a Tyr-kinase domain (aa 118-372). Over aa 72-320, human STYK1 is 77% and 83% identical to mouse and canine STYK1, respectively.
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FAQs
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