Human TAFA4/FAM19A4 Alexa Fluor® 350-conjugated Antibody
Human TAFA4/FAM19A4 Alexa Fluor® 350-conjugated Antibody Summary
Accession # Q96LR4
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
TAFA4 (also FAM19A4) is a secreted, 12 kDa member of the FAM19/TAFA family of chemokine-like proteins (1). It is synthesized as a 140 amino acid (aa) precursor that contains a 35 aa signal sequence and a 105 aa mature chain. Like other members of the FAM19/TAFA family, with the exception of TAFA5, mature TAFA1 contains 10 regularly spaced cysteine residues that follow the pattern Cx7CCx13CxCx14Cx11Cx4Cx5Cx10C, where C represents a conserved cysteine residue and x represents any noncysteine amino acid (1). Human TAFA4 is 90% aa identical to mouse TAFA4 (1). Real-time PCR analysis indicates that TAFA4 mRNA expression is restricted to the central nervous system (CNS), with the highest level in the thalamus (1). TAFAs may modulate immune responses in the CNS by functioning as brain specific chemokines and may act with other chemokines to optimize the recruitment and activity of immune cells in the CNS (1). TAFAs may represent a novel class of neurokines that act as regulators of immune nervous cells (1, 2). TAFAs may also control axonal sprouting following brain injury (1).
- Tang, Y.T. et al. (2004) Genomics 83:727.
- Benveniste, E. (1998) Cytokine Growth Factor Rev. 9:259.
No product specific FAQs exist for this product, however you mayView all Antibody FAQs
Reviews for Human TAFA4/FAM19A4 Alexa Fluor® 350-conjugated Antibody
There are currently no reviews for this product. Be the first to review Human TAFA4/FAM19A4 Alexa Fluor® 350-conjugated Antibody and earn rewards!
Have you used Human TAFA4/FAM19A4 Alexa Fluor® 350-conjugated Antibody?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image