Human TAP1 (NP_000584) VersaClone cDNA

Name: Human TAP1 (NP_000584) VersaClone cDNA
Brand: R&D Systems
SKU: RDC2269
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC2269

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Product Documents

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Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species

Human

Accession Number

NP_000584

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: TAP1

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.

Long Name

Transporter 1, ATP Binding Cassette Subfamily B Member

Alternate Names

ABC Transporter, MHC 1, ABC17, ABCB2, Ham1, Peptide Transporter TAP1, PSF1, RING4, TAP1N

Entrez Gene IDs

6890 (Human); 21354 (Mouse); 24811 (Rat)

Gene Symbol

TAP1

UniProt

NP_000584

Additional TAP1 Products

Product Documents for Human TAP1 (NP_000584) VersaClone cDNA

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Certificate of Analysis

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Product Specific Notices for Human TAP1 (NP_000584) VersaClone cDNA

For research use only

Related Research Areas

Cancer Biomarkers

Diabetes

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