Human TBX20 Alexa Fluor® 488-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: TBX20

TBX20 (T-box transcription factor 20) is a transcriptional activator and repressor that is essential for cardiac development and to adult cardiomyocyte function. Mutation in humans or mice can result in congenital heart disease, including septation, chamber, and valvulogenesis defects and dilated cardiomyopathy. These include atrial septal defect 4 (ASD4). The 447 amino acid (aa) human TBX20 contains a T-box DNA binding domain at aa 109-228. Between aa 1-116, human TBX20 shares 96% aa sequence identity with mouse TBX20. One isoform that is truncated at aa 297 has been described.

Product Datasheets