Human TMEFF1/Tomoregulin-1 Alexa Fluor® 594-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB1919T-100UG

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Human TMEFF1/Tomoregulin-1 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human TMEFF1/Tomoregulin‑1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no  cross-reactivity with recombinant mouse TMEFF1 or recombinant human TMEFF2 is observed.
Source
Monoclonal Mouse IgG2a Clone # 249511
Purification
Protein A or G purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human TMEFF1/Tomoregulin‑1
Ser40-Thr328
Accession # Q8IYR6
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: TMEFF1/Tomoregulin-1

TMEFF1 (Transmembrane protein with EGF-like and two Follistatin-like domains 1), also known as tomoregulin 1 is a type I transmembrane glycoprotein that contains two follistatin modules and an EGF domain in its extracellular domain, a transmembrane domain and a short cytoplasmic tail. The extracellular domain can be released as a soluble protein. TMEFF1 selectively regulates nodal but not activin signaling through direct binding to the nodal co-receptor, Cripto.

Long Name
Transmembrane Protein with EFG-like and two Follistatin-like Domains
Entrez Gene IDs
8577 (Human); 230157 (Mouse)
Alternate Names
C9orf2; H7365member 1; TMEFF1; Tomoregulin1; Tomoregulin-1; TR-1; Transmembrane protein with EGF-like and one follistatin-like domain; transmembrane protein with EGF-like and two follistatin-like domains 1

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