Tetraspanin-8 (TSPAN8), also known as TM4SF3 and human tumor-associated antigen CO-0029, is a member of the transmembrane 4 (tetraspanin) superfamily. It is a cell surface 27 - 34 kDa protein with intracellular N- and C-termini, 4 transmembrane segments and a large extracellular loop (LEL) domain from aa 106 - 206. TSPAN8 is involved in integrin-mediated cell motility, metastasis, cell proliferation and differentiation, and is over-expressed in carcinomas including hepatocellular carcinoma and colon cancer. Polymorphisms have variably been associated with type II diabetes, bipolar disorder and schizophrenia.
Human TSPAN8 (NP_004607) VersaClone cDNA
R&D Systems | Catalog # RDC0195
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: TSPAN8
Long Name
Tetraspanin 8/Transmembrane 4 Superfamily, Member 3
Alternate Names
CO-029, TM4SF3
Gene Symbol
TSPAN8
UniProt
Additional TSPAN8 Products
Product Documents for Human TSPAN8 (NP_004607) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human TSPAN8 (NP_004607) VersaClone cDNA
For research use only
Related Research Areas
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