Tyk2 belongs to the Janus family of intracellular tyrosine kinases that are activated by receptors for many cytokines. Activation of Tyk2 occurs via phosphorylation at two adjacent tyrosine residues within the kinase domain. Tyk2 is required for interferon-mediated tyrosine phosphorylation of STAT3 and interferon a receptor 1. Mice lacking Tyk2 are susceptible to parasitic infection but resistant to autoimmune arthritis.
Human Tyk2 (NP_003322.3) VersaClone cDNA
R&D Systems | Catalog # RDC3610
Loading...
Loading...
Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: Tyk2
Long Name
Protein tyrosine kinase 2
Alternate Names
EC 2.7.10, EC 2.7.10.2, JTK1, non-receptor tyrosine-protein kinase TYK2, tyrosine kinase 2
Gene Symbol
TYK2
UniProt
Additional Tyk2 Products
Product Documents for Human Tyk2 (NP_003322.3) VersaClone cDNA
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human Tyk2 (NP_003322.3) VersaClone cDNA
For research use only
Related Research Areas
Customer Reviews for Human Tyk2 (NP_003322.3) VersaClone cDNA
There are currently no reviews for this product. Be the first to review Human Tyk2 (NP_003322.3) VersaClone cDNA and earn rewards!
Have you used Human Tyk2 (NP_003322.3) VersaClone cDNA?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review
Loading...
Associated Pathways
Jak/STAT Signaling Pathway
Th1 Differentiation Pathway
Th17 Differentiation Pathway
