Members of the UNC5H family are best known as receptors for the axon guidance molecule netrin. Structurally, UNC5Hs have two Ig and two thrombospondin type 1 domains in their extracellular region, and a conserved ZU-5 domain, a deleted in colorectal cancer (DCC)-binding domain, and a C-terminal death domain in their cytoplasmic region. In general, they mediate the chemorepulsive effects of netrin, while the other netrin receptor subtype, DCC, mediates attraction. Members of the UNC5H family have also been implicated as tumor suppressors and regulators of apoptosis.
Human UNC5H1 (NP_588610) VersaClone cDNA
R&D Systems | Catalog # RDC1827
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: UNC5H1
Long Name
Netrin Receptor UNC5A
Alternate Names
UNC5A
Gene Symbol
UNC5A
UniProt
Additional UNC5H1 Products
Product Documents for Human UNC5H1 (NP_588610) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human UNC5H1 (NP_588610) VersaClone cDNA
For research use only
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