Human Vitamin D BP Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB3778S Datasheet / COA / SDS

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FAB3778S-100UG

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All Vitamin D BP Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human Vitamin D BP Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human plasma-derived Vitamin D BP in direct ELISAs and Western blots.

Source

Monoclonal Mouse IgG2b Clone # 359501

Purification

Protein A or G purified

Immunogen

Human plasma-derived Vitamin D BP
Accession # P02774

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Vitamin D BP

Vitamin D BP (VitD BP), also called VDB, DBP, Group Specific Component (Gc) or macrophage-activating factor (DBP- or Gc-MAF), is a member of the albumin family. These plasma/body fluid proteins have a conserved pattern of cysteine motifs that form binding domains. VitD BP is predominantly produced by hepatic parenchymal cells. It transports VitD, activates macrophages and osteoclasts, and enhances C5a chemotactic activity. Over 80 variant alleles have been identified, some of which correlate with osteoporosis or prostate cancer. Human and mouse VitD BP share 78% aa identity.

Long Name

Vitamin D Binding Protein

Entrez Gene IDs

2638 (Human); 14473 (Mouse); 24384 (Rat)

Alternate Names

DBP; DBP/GC; DBP-MAF; DBPVDBG; EC 6.3.1.5; Gc; gc-globulin; Gc-MAF; GRD3; group-specific component (vitamin D binding protein); Group-specific component; hDBP; VDB; VDBG; VDBP; Vitamin D BP; vitamin D-binding alpha-globulin; vitamin D-binding protein