Human ZP2 (NP_003451) VersaClone cDNA

R&D Systems | Catalog # RDC2030

R&D Systems
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Key Product Details

Species

Human

Accession Number

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Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: ZP2

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in secondary binding and penetration of acrosome-reacted spermatozoa. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. [provided by RefSeq]

Long Name

Zona Pellucida Glycoprotein 2 (Sperm Receptor)

Alternate Names

Zona Pellucida Protein A, Zp-2, ZPA

Entrez Gene IDs

7783 (Human); 22787 (Mouse); 81828 (Rat)

Gene Symbol

ZP2

UniProt

Additional ZP2 Products

Product Documents for Human ZP2 (NP_003451) VersaClone cDNA

Certificate of Analysis

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Product Specific Notices for Human ZP2 (NP_003451) VersaClone cDNA

For research use only

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