Hydroxy Dynasore

   
Product Datasheet
Catalog Number:5364
Alternate Names:Dyngo 4a
Chemical Name:3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5)-trihydroxyphenyl)methylene]hydrazide
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Biological Activity
Dynamin inhibitor (IC50 values are 0.38 and 2.6 μM for dynamin 1 and 2 respectively). Inhibits dynamin-mediated endocytosis in multiple cell types and reduces synaptic vesicle endocytosis in vitro. Prevents botulinum A internalization in hippocampal neurons. Also protects against botulinum A-induced muscle paralysis in rats. Analog of Dynasore (Cat. No. 2897).
Technical Data
  • M.Wt:
    338.31
  • Formula:
    C18H14N2O5
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    1256493-34-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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