Potent and selective BRD9 inhibitor (pIC50
= 7.3). Exhibits >70-fold selectivity for BRD9 over a panel of 34 other bromodomains and >700-fold selectivity over the BET family. Downregulates CLEC
1 genes in Kasumi-1 cells.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the I-BRD9 probe summary
on the SGC website.
Discovery of I-BRD9, a selective cell active chemical probe for bromodomain containing protein 9 inhibition.
Theodoulou et al.