CBP/p300 bromodomain inhibitor (IC50
values are 0.142-0.17 and 0.625 μ
M for CBP and p300 respectively). Selective for CBP and p300 over ATAD2, BAZ2B, BRD2(2), BRD4(1), PB1(5), PCAF, PHIP(2) and TIF1α
bromodomains in a BLI assay. Accelerates FRAP recovery in cells at a concentration of 1 μ
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the I-CBP 112 probe summary
on the SGC website.
Bromodomains and their pharmacological inhibitors.
Gallenkamp et al.