ICG-d7

Tocris Bioscience | Catalog # 7749

Near-infrared (NIR) fluorescent dye; partially deuterated form of Indocyanine Green (Cat. No. 7510), suitable for in vivo imaging.
Tocris Bioscience
Discontinued Product
7749 has been discontinued. View all Fluorescent Dyes products.

Key Product Details

Description

Near-infrared (NIR) fluorescent dye; partially deuterated form of Indocyanine Green (Cat. No. 7510), suitable for in vivo imaging.

Wavelength

Excitation = 794 nm, Emission = 818 nm
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Product Description

Key information:

ICG-d7 is a partially deuterated form of near-infrared fluorescent dye Indocyanine Green (ICG; Cat. No. 7510).

Application: Fluorescence microscopy, in vivo imaging.

Properties and Photophysical Data: ICG-d7 operates in the 700 - 900 nm wavelength range; also exhibits fluorescence emission in the shortwave infrared window (SWIR; 1,000 - 2,000 nm) which enables in vivo imaging. ICG-d7 shows improved stability in aqueous solutions over ICG with the same fluorescence brightness, and similar absorption and emission maxima in both DMSO and FBS. Excitation and emission maxima (λ) are 794 nm and 818 nm, respectively; quantum yield = 0.21; extinction coefficient = 228,000 M-1cm-1.

Licensing Information

Sold under license from the University of Notre Dame

Optical Data

ICG-d7 Dye Spectra
Emission Color Near-IR
λabs 794 nm
λem 818 nm
Extinction Coefficient (ε) 228000 M-1cm-1
Quantum Yield (φ) 0.21
Application Fluorescence Microscopy, In Vivo Imaging
Alternative For Indocyanine green

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Product Specifications for ICG-d7

Molecular Weight

782.01

Formula

C43H40D7N2O6S2Na

Storage

Store at -20°C

Purity

≥95% (HPLC)

Chemical Name

Sodium 4-(2-((1E,3E,5E,7Z)-7-(1,1-Dimethyl-3-(4-sulfonatobutyl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene)hepta-1,3,5-trien-1-yl-1,2,3,4,5,6,7-d7)-1,1-dimethyl-1H-benzo[e]indol-3-ium-3-yl)butane-1-sulfonate

CAS Number

2861905-57-7

InChI Key

MOFVSTNWEDAEEK-ZMRQXZMGSA-M

SMILES

CC1(C)/C(N(CCCCS(=O)(O[Na])=O)C2=C1C3=CC=CC=C3C=C2)=C(/C([2H])=C(/C([2H])=C(/C([2H])=C(C4=[N+](CCCCS([O-])(=O)=O)C5=C(C6=CC=CC=C6C=C5)C4(C)C)\[2H])[2H])[2H])[2H]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 7.82 10
DMSO 7.82 10

Preparing Stock Solutions for ICG-d7

The following data is based on the product molecular weight 782.01.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.79 mL 63.94 mL 127.88 mL
0.5 mM 2.56 mL 12.79 mL 25.58 mL
1 mM 1.28 mL 6.39 mL 12.79 mL
5 mM 0.26 mL 1.28 mL 2.56 mL

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Background References

References are publications that support the biological activity of the product.

Product Documents for ICG-d7

Certificate of Analysis

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Product Specific Notices for ICG-d7

For research use only

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