ICI 204,448 hydrochloride

Tocris Bioscience | Catalog # 0822

κ agonist, acts peripherally
Tocris Bioscience

Key Product Details

Description

κ agonist, acts peripherally
View all Kappa Opioid Receptor Agonists »

Product Description

ICI 204,448 hydrochloride is a peripherally acting κ agonist.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Product Specifications for ICI 204,448 hydrochloride

Molecular Weight

501.84

Formula

C23H26Cl2N2O4.HCl

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(RS)-[3-[1-[[(3,4-Dichlorophenyl)acetyl]methylamino]-2-(1-pyrrolidinyl)ethyl]phenoxy]acetic acid hydrochloride

CAS Number

121264-04-8

PubChem ID

129407

InChI Key

FNDGLVOYAQNQPE-UHFFFAOYSA-N

SMILES

Cl.CN(C(CN1CCCC1)C1=CC(OCC(O)=O)=CC=C1)C(=O)CC1=CC(Cl)=C(Cl)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 100

Preparing Stock Solutions for ICI 204,448 hydrochloride

The following data is based on the product molecular weight 501.84.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.99 mL 9.96 mL 19.93 mL
5 mM 0.40 mL 1.99 mL 3.99 mL
10 mM 0.20 mL 1.00 mL 1.99 mL
50 mM 0.04 mL 0.20 mL 0.40 mL

Calculators

Calculate the mass, volume, or concentration required for a solution.

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

x
=
x

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 6 publications citing the usage of this product.

Product Documents for ICI 204,448 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ICI 204,448 hydrochloride

For research use only

Citations for ICI 204,448 hydrochloride

Customer Reviews for ICI 204,448 hydrochloride (1)

5 out of 5
1 Customer Rating
5 Stars
100%
4 Stars
0%
3 Stars
0%
2 Stars
0%
1 Stars
0%

Have you used ICI 204,448 hydrochloride?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

Customer Images

Showing  1 - 1 of 1 review Showing All
Filter By:
Clear Filters X
  • Mouse EFS model
    Name: John Broad
    Species: Mouse
    Assay Type: In Vitro
    Verified Customer | Posted 01/05/2018
    Inhibited mouse GI EFS smooth muscle contractions
    ICI 204,448 hydrochloride 0822

There are no reviews that match your criteria.

Showing  1 - 1 of 1 review Showing All