Chemical Name:N-(Tricyclo[126.96.36.199,7]dec-1-ylmethyl)-1,5-pentanediamine dihydrobromide
Biological Activity Voltage-dependent open-channel blocker of AMPA receptors. Selective between subtypes; blocks GluR2 subunit-lacking (Ca2+-permeable) receptors more potently than GluR2-containing receptors. Also potently blocks NMDA receptor channels. Less sensitive than IEM 1460 (Cat. No. 1460) at a holding potential between -40 and -80mV.
Soluble to 100 mM in water and to 50 mM in DMSO
Store at RT
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For batch specific data refer to the Certificate of Analysis.
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