IEM 1754 dihydrobromide

Catalog # Availability Size / Price Qty
4199/10
4199/50
AMPA Receptor Blockers Small Molecule
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Description: Voltage-dependent, open-channel AMPA blocker

Chemical Name: N-(Tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1,5-pentanediamine dihydrobromide

Purity: ≥98%

Product Details
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Biological Activity

Voltage-dependent open-channel blocker of AMPA receptors. Selective between subtypes; blocks GluA2 subunit-lacking (Ca2+-permeable) receptors more potently than GluA2-containing receptors. Also potently blocks NMDA receptor channels. Less sensitive than IEM 1460 (Cat. No. 1460) at a holding potential between -40 and -80mV.

Technical Data

M.Wt:
412.25
Formula:
C16H30N2.2HBr
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
162831-31-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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