IEM 1754 dihydrobromide

Discontinued Product

4199 has been discontinued.
View all AMPA Receptor Blockers products.
IEM 1754 dihydrobromide | CAS No. 162831-31-4 | AMPA Receptor Blockers
1 Image
Description: Voltage-dependent, open-channel AMPA blocker

Chemical Name: N-(Tricyclo[,7]dec-1-ylmethyl)-1,5-pentanediamine dihydrobromide

Purity: ≥98%

Product Details

Biological Activity

IEM 1754 dihydrobromide is a voltage-dependent open-channel blocker of AMPA receptors. Selective between subtypes; blocks GluA2 subunit-lacking (Ca2+-permeable) receptors more potently than GluA2-containing receptors. Also potently blocks NMDA receptor channels. Less sensitive than IEM 1460 (Cat. No. 1460) at a holding potential between -40 and -80mV.

Technical Data

Soluble to 100 mM in water and to 50 mM in DMSO
Store at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Molarity Calculator


*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).


No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for IEM 1754 dihydrobromide

There are currently no reviews for this product. Be the first to review IEM 1754 dihydrobromide and earn rewards!

Have you used IEM 1754 dihydrobromide?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.