IL-10 R beta Antibody (MM0360-8R24) - Azide and BSA Free

Novus Biologicals | Catalog # NBP2-11654

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, Block/Neutralize

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # MM0360-8R24

Format

Azide and BSA Free
View all IL-10 R beta Primary Antibodies »

Product Specifications

Immunogen

Human recombinant IL-10 R beta (extracellular domain)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for IL-10 R beta Antibody (MM0360-8R24) - Azide and BSA Free

Western Blot: IL-10 R beta Antibody (MM0360-8R24)Azide and BSA Free [NBP2-11654]

Western Blot: IL-10 R beta Antibody (MM0360-8R24)Azide and BSA Free [NBP2-11654]

Western Blot: IL-10 R beta Antibody (MM0360-8R24) - Azide and BSA Free [NBP2-11654] - Lysate of human placenta tissue with mouse anti-human IL-10 R beta antibody.

Applications for IL-10 R beta Antibody (MM0360-8R24) - Azide and BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IL-10 R beta

IL10RB, also known as Interleukin-10 receptor subunit beta, is a 325 amino acid protein that is 37 kDa; belongs to the type II cytokine receptor family; cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IL29; and its co-expression with IL10RA proteins is needed for IL10-induced signal transduction. This protein is currently being studied for research on several diseases and disorders including inflammatory bowel disease 25, early onset, autosomal recessive, hepatitis b virus, inflammatory bowel disease, hepatitis b, interferon, respiratory syncytial virus bronchiolitis, graft versus host disease, ulcerative colitis crohn's disease, anaplastic large cell lymphoma, secondary hyperparathyroidism, mumps, systemic lupus erythematosus, measles, bronchiolitis, rubella, cblc, lupus erythematosus, rheumatoid arthritis, colitis, and tumors. Interactions with IL10RB have been shown to involve IL22, UCN3, IL10RA, IL28A, and IL10 in cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, toxoplasmosis, tuberculosis, antioxidant action of vitamin-C, immune response IL-22 signaling pathway, and molecular mechanisms of cancer pathway.

Long Name

Interleukin 10 Receptor beta

Alternate Names

CDw210b, CRFB4, D21S58, IL-10R2, IL-10Rb, IL10R beta, IL10RB

Gene Symbol

IL10RB

UniProt

Q08334

Additional IL-10 R beta Products

Product Documents for IL-10 R beta Antibody (MM0360-8R24) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for IL-10 R beta Antibody (MM0360-8R24) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs

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Associated Pathways

Jak/STAT Signaling Pathway Jak/STAT Signaling Pathway Thumbnail