IL-11 Ra (Interleukin-11 receptor alpha) is a widely expressed transmembrane protein that associates with gp130 to form a functional receptor complex for the cytokine IL-11. gp130 also functions as a subunit in the receptors for Cardiotrophin-1, CNTF, IL-6, IL-27, IL-31, LIF, and Oncostatin M. IL-11 Ra plays a role in female reproduction and the survival of oligodendrocytes and colonic epithelial cells. It enhances osteoclast differentiation and bone remodeling but inhibits adipocyte differentiation. Soluble IL-11 Ra confers IL-11 responsiveness to cells expressing gp130, while in cells expressing transmembrane IL-11 Ra and gp130, soluble IL-11 Ra acts as an IL-11 antagonist.
Recombinant Rat IL-11R alpha His Protein
Novus Biologicals | Catalog # NBP2-52394
![SDS-PAGE: Recombinant Rat IL-11R alpha His Protein [NBP2-52394]](https://resources.rndsystems.com/images/products/IL-11-R-alpha-Recombinant-Protein-SDS-Page-NBP2-52394-img0001.jpg "SDS-PAGE: Recombinant Rat IL-11R alpha His Protein [NBP2-52394]")
Loading...
Key Product Details
Source
Baculovirus
Tag
His
Applications
SDS-PAGE
Loading...
Product Specifications
Description
A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 24-371 of Rat IL-11 R alpha
Source:Baculovirus
Amino Acid Sequence: TPCPQAWGPP GVQYGQPGRP VMLCCPGVNA GTPVSWFRDG DSRLLQGPDS GLGHRLVLAQ VDSRDEGTYV CRTLDGVFGG MVTLKLGSPP ARPEVSCQAV DYENFSCTWS PGRVSGLPTR YLTSYRKKTL PGAESQRESP STGPWPCPQD PLEASRCVVH GAEFWSEYRI NVTEVNPLGA STCLLDVRLQ RILRPDPPQG LRVESVPGYP RRLHASWTYP ASWRRQPHFL LKFRLQYRPA QHPAWSTVEP IGLEELITDA VAGLPHAVRV SARDFLDAGT WSAWSPEAWG TPSTGPLRDE VPDGSRGHEQ KLEAAAQEDS PAPPSPSLQP DPRPLDHRDP LEQVAVLAVE HHHHHH
Purity
>85%, by SDS-PAGE
Endotoxin Level
< 1.0 EU per 1 microgram of protein (determined by LAL method)
Predicted Molecular Mass
39.2 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Protein / Peptide Type
Recombinant Protein
Scientific Data Images for Recombinant Rat IL-11R alpha His Protein
SDS-PAGE: Recombinant Rat IL-11R alpha His Protein [NBP2-52394]
SDS-Page: Recombinant Rat IL-11 R alpha Protein [NBP2-52394] - 15% SDS Page (3 ug)Formulation, Preparation, and Storage
NBP2-52394
| Formulation | PBS (pH 7.4), 10% glycerol |
| Preservative | No Preservative |
| Concentration | 0.25 mg/ml |
| Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Background: IL-11 R alpha
Long Name
Interleukin 11 Receptor alpha
Alternate Names
IL-11Ra, IL11R alpha, IL11RA
Gene Symbol
IL11RA
Additional IL-11 R alpha Products
Product Documents for Recombinant Rat IL-11R alpha His Protein
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Recombinant Rat IL-11R alpha His Protein
This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.
Related Research Areas
Customer Reviews for Recombinant Rat IL-11R alpha His Protein
There are currently no reviews for this product. Be the first to review Recombinant Rat IL-11R alpha His Protein and earn rewards!
Have you used Recombinant Rat IL-11R alpha His Protein?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review
Loading...