Human IL-22 R (also known as CRF2-9 and IL-22 Ra1), is a 557 amino acid (aa) type I transmembrane protein that contains a 188 aa extracellular region, a 23 aa transmembrane segment, and a 346 aa cytoplasmic domain. The extracellular region contains two fibronectin type III domains.
IL-22R alpha 1 Antibody (496504) [Allophycocyanin]
Novus Biologicals | Catalog # FAB4294A
Key Product Details
Species Reactivity
Mouse
Applications
Western Blot, Neutralization
Label
Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)
Antibody Source
Monoclonal Rat IgG2A Clone # 496504
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Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IL-22 R alpha 1
Thr18-Ala228
Accession # Q80XZ4
Thr18-Ala228
Accession # Q80XZ4
Specificity
Detects mouse IL-22 R alpha 1 in direct ELISAs and Western blots. Shows approximately 20% cross‑reactivity with recombinant human (rh) IL-22 R and no cross-reactivity with rhIL-20 R alpha, rhIL-20 R beta, or recombinant mouse IL-22BP.
Clonality
Monoclonal
Host
Rat
Isotype
IgG2A
Applications for IL-22R alpha 1 Antibody (496504) [Allophycocyanin]
Application
Recommended Usage
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Neutralization
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Formulation
PBS
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: IL-22 R alpha 1
Long Name
Interleukin 22 Receptor
Alternate Names
CRF2-9, IL-22Ra1, IL-TIF-R1, IL22R alpha 1, IL22RA1
Gene Symbol
IL22RA1
Additional IL-22 R alpha 1 Products
Product Documents for IL-22R alpha 1 Antibody (496504) [Allophycocyanin]
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for IL-22R alpha 1 Antibody (496504) [Allophycocyanin]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Related Research Areas
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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