IL‑28A/Interferon-lambda 2) is a type III interferon that is upregulated in response to viral infection. It acts primarily on epithelial cells through a receptor complex that contains IL-10 R beta and IL-28 R alpha/IFN-lambda R1. IL-28A promotes the Th1 polarization of dendritic cells in the airway (e.g. production of IL-12 p70 and IFN-gamma) and inhibits Th2 and Th17 mediated inflammation. In the liver, however, the IL-28A induced Th1 cytokine response contributes to inflammation in T cell mediated hepatitis. IL-28A additionally exhibits anti-tumor activity, in part by enhancing IL-12 dependent anti-tumor CTL responses. In contrast, it is upregulated in invasive bladder cancer where it promotes tumor cell migration.
Human IL-28A/IFN-lambda 2 ELISA Kit (Colorimetric)
Novus Biologicals | Catalog # NBP3-06787
Key Product Details
Sample Type & Volume Required Per Well
Sensitivity
Assay Range
Product Specifications
Assay Type
Kit Type
Species
Specificity
Precision
Intra-Assay Precision (Precision within an assay) 4.88
Inter-Assay Precision (Precision between assays) 5.27
Recovery for Human IL-28A/IFN-lambda 2 ELISA Kit (Colorimetric)
Recovery
Linearity
Scientific Data Images for Human IL-28A/IFN-lambda 2 ELISA Kit (Colorimetric)
ELISA: Human IL-28A/IFN-lambda 2 ELISA Kit (Colorimetric) [NBP3-06787] -
ELISA: Human IL-28A/IFN-lambda 2 ELISA Kit (Colorimetric) [NBP3-06787] - Standard Curve ReferenceKit Contents for Human IL-28A/IFN-lambda 2 ELISA Kit (Colorimetric)
- Biotinylated Detection Ab Diluent
- Concentrated Biotinylated Detection Ab (100x)
- Concentrated HRP Conjugate (100x)
- Concentrated Wash Buffer (25x)
- HRP Conjugate Diluent
- Micro ELISA Plate (Dismountable)
- Plate Sealer
- Product Manual
- Reference Standard
- Sample Diluent
- Stop Solution
- Substrate Reagent
Preparation and Storage
Shipping
Stability & Storage
Background: IL-28A/IFN-lambda 2
Long Name
Alternate Names
Gene Symbol
Additional IL-28A/IFN-lambda 2 Products
Product Documents for Human IL-28A/IFN-lambda 2 ELISA Kit (Colorimetric)
Certificate of Analysis
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Product Specific Notices for Human IL-28A/IFN-lambda 2 ELISA Kit (Colorimetric)
This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.
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