Chemical Name: 5-[2-(Imidazol-4-yl)ethyl]isothiourea dihydrobromide
Biological Activity An extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration. Also available as part of the Histamine H3 Receptor Tocriset™.
Soluble to 100 mM in water
Store at RT
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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