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IMP 2373

Catalog #: 8171 Datasheet / COA / SDS
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8171/2

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IMP 2373 | General Laboratory Research Reagent
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Description: pan-DUB activity-based probe with alkyne click handle

Chemical Name: 4-(1-Cyanopyrrolidine-3-carbonyl)-N-[(4-ethynylphenyl)methyl]-1-methylpyrrole-2-carboxamide

Purity: ≥98%

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Biological Activity

IMP 2373 is a pan-deubiquitinase (pan-DUB) activity-based probe with alkyne click handle. IMP 2373 interacts with more than 35 DUBs in diverse cell lines and across a range of non-toxic concentrations. IMP 2373 can be used to monitor changes in intracellular DUB activity in live cells during pharmacological inhibition and in vivo during MYC deregulation in a model of B cell lymphoma.

Technical Data

M.Wt:
360.42
Formula:
C21H20N4O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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