Potent monoamine uptake inhibitor. Inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET) (Ki
values are 0.42, 1.7 and 5.8 nM respectively). Centrally active following systemic administration in vivo
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Design, synthesis, and monoamine transporter binding site affinities of methoxy derivatives of indatraline.
Gu et al.
Neurochemical profile of Lu 19-005, a potent inhibitor of uptake of dopamine, noradrenaline and serotonin.
Hyttel and Larsen
Effects of the long-acting monoamine reuptake inhibitor indatraline on cocaine self-administration in rhesus monkeys.
Negus et al.