Integrin alpha 2/CD49b Antibody (S06-7A5)

Name: Integrin alpha 2/CD49b Antibody (S06-7A5)
Brand: Novus Biologicals
SKU: NBP3-19666
Price: 559 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-19666

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Product Documents

Recombinant Monoclonal Antibody

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Product Specifications
Scientific Data
Applications
Preparation & Storage
Background
Product Documents
Specific Notices
Research Areas

Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S06-7A5 expressed in HEK293

View all Integrin alpha 2/CD49b Primary Antibodies »

Product Specifications

Immunogen

A synthetic peptide of human Integrin alpha 2/CD49b (Uniprot # P17301)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

150 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Integrin alpha 2/CD49b Antibody (S06-7A5)

Western Blot: Integrin alpha 2/CD49b Antibody (S06-7A5) [NBP3-19666]

Western Blot: Integrin alpha 2/CD49b Antibody (S06-7A5) [NBP3-19666] - Western blot detection of Integrin alpha 2/CD49b in Hela cell lysates using NBP3-19666 (1:1000 diluted). Predicted band size: 129kDa. Observed band size: 150kDa.

Applications for Integrin alpha 2/CD49b Antibody (S06-7A5)

Application

Recommended Usage

Western Blot

1/2000-1/10000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Integrin alpha 2/CD49b

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.

Alternate Names

CD49b, ITGA2, VLA-2 alpha

Gene Symbol

ITGA2

Additional Integrin alpha 2/CD49b Products

Product Documents for Integrin alpha 2/CD49b Antibody (S06-7A5)

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Certificate of Analysis

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Product Specific Notices for Integrin alpha 2/CD49b Antibody (S06-7A5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.