Human Integrin alpha 2/CD49b ELISA Kit (Colorimetric)

Key Product Details

Product Specifications

Precision

Intra-Assay Precision (Precision within an assay) %CV 10 (example only; lot dependent)

Inter-Assay Precision (Precision between assays) %CV 12 (example only; lot dependent)

Kit Contents for Human Integrin alpha 2/CD49b ELISA Kit (Colorimetric)

• Assay Diluent A
• Assay Diluent B
• Detection Reagent A
• Detection Reagent B
• Instruction manual
• Plate sealer for 96 wells
• Pre-coated ready to use 96-well strip plate
• Standard
• Standard Diluent
• Stop Solution
• TMB Substrate
• Wash Buffer (30 x concentrate)

Preparation and Storage

Background: Integrin alpha 2/CD49b

Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. They are responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells.

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Product Documents for Human Integrin alpha 2/CD49b ELISA Kit (Colorimetric)