Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 437216
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Product Specifications

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant human Integrin  beta 6
Gly22-Asn707
Accession # P18564

Specificity

Detects human Integrin  beta 6 in direct ELISAs and Western blots. In Western blots (under reducing conditions), 40% cross‑reactivity with recombinant human (rh) Integrin  beta 2 is observed and no cross-reactivity with rhIntegrin beta 1, 3, 5, 7, or 8 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Integrin beta 6 Antibody (437216) [DyLight 405]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Integrin beta 6

Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion

Alternate Names

ITGB6

Gene Symbol

ITGB6

Additional Integrin beta 6 Products

Product Documents for Integrin beta 6 Antibody (437216) [DyLight 405]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Integrin beta 6 Antibody (437216) [DyLight 405]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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