Recombinant Human IPP Protein

Name: Recombinant Human IPP Protein
Brand: Novus Biologicals
SKU: NBC1-18418
Price: 269 USD
Availability: InStock

Novus Biologicals | Catalog # NBC1-18418

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Product Specifications
Scientific Data
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Applications

SDS-PAGE

View all IPP Proteins and Enzymes »

Product Specifications

Description

An un-tagged recombinant protein corresponding to the amino acids 1-157 of Human E.coli IPP

Source: E.coli

Amino Acid Sequence: MANEDCPKAA DSPFSSDKHA QLILAQINKM RNGQHFCDVQ LQVGQESFKA HRLVLAASSP YFAALFTGGM KESSKDVVPI LGIEAGIFQI LLDFIYTGIV NIGVNNVQEL IIAADMLQLT EVVHLCCEFL KGQIDPLNCI GIFQFSEQIA CHDLLEF

Purity

>95%, by SDS-PAGE

Predicted Molecular Mass

17.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Scientific Data Images for Recombinant Human IPP Protein

SDS-PAGE: Recombinant Human IPP Protein [NBC1-18418]

SDS-Page: IPP Protein [NBC1-18418] - IPP-POZ domain, 17.3 kDa (157 aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Formulation, Preparation, and Storage

NBC1-18418

Formulation	10 mM HEPES buffer (pH7.4), 25 mM NaCl
Preservative	No Preservative
Concentration	1 mg/ml
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: IPP

Intracisternal A particle-promoted polypeptide(IPP) is a 66kDa protein(584 amino acids), which contains an N-terminal POZ protein-protein interaction domain and a C-terminla kelch repeat domain consisting of six tandem arranged repeats. The POZ domain(also called BTB domain) is present near the N-terminus of a fraction of zinc finger proteins and in protein that contain the pfam01344 motif such as kelch and pox virus proteins. The BTB/POZ domain mediates homomeric dimerization and in some instances heteromeric dimerization. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-coR and SMRT. IPP-POZ domain(1-157aa) was overexpressed in E.coli and purified by using conventional chromatography techniques

Alternate Names

actin-binding protein IPP, intracisternal A particle-promoted polypeptideKLHL27Kelch-like protein 27

Gene Symbol

IPP

Additional IPP Products

Product Documents for Recombinant Human IPP Protein

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Product Specific Notices for Recombinant Human IPP Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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