IQ 1

Tocris Bioscience | Catalog # 4713

Enables Wnt/β-catenin-driven expansion of ESCs; prevents spontaneous differentiation
Tocris Bioscience
Discontinued Product
4713 has been discontinued. View all Compounds for Induced Pluripotent Stem Cells products.

Key Product Details

Description

Enables Wnt/β-catenin-driven expansion of ESCs; prevents spontaneous differentiation
View all Compounds for Induced Pluripotent Stem Cells »

Product Description

IQ 1 is a maintains embryonic stem cell (ESC) pluripotency in Wnt3a-treated cells; enables Wnt/β-catenin-driven expansion of mouse ESCs and prevents spontaneous differentiation. Upregulates expression of Oct4 and Sox2 transcription factors. Binds to serine/threonine phosphatase PP2A and prevents PP2A/Nkd interaction.

Product Specifications for IQ 1

Molecular Weight

362.42

Formula

C21H22N4O2

Storage

Store at -20°C

Purity

≥99% (HPLC)

Chemical Name

2-[2-(4-Acetylphenyl)diazenyl]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)acetamide

CAS Number

331001-62-8

PubChem ID

56801

InChI Key

XTZNCVSCVHTPAI-UHFFFAOYSA-N

SMILES

CC(C(C=C3)=CC=C3/N=N/C(C(N)=O)=C2\C1=CC=CC=C1CC(C)(C)N2)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 36.24 100
Ethanol 7.25 20

Preparing Stock Solutions for IQ 1

The following data is based on the product molecular weight 362.42.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.76 mL 13.80 mL 27.59 mL
5 mM 0.55 mL 2.76 mL 5.52 mL
10 mM 0.28 mL 1.38 mL 2.76 mL
50 mM 0.06 mL 0.28 mL 0.55 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

Product Documents for IQ 1

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for IQ 1

For research use only

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