Irbesartan

Tocris Bioscience | Catalog # 5798

Potent AT1 antagonist
Tocris Bioscience

Key Product Details

Description

Potent AT1 antagonist
View all Angiotensin AT1 Receptor Antagonists »

Product Description

Irbesartan is a potent angiotensin II type 1 receptor (AT1) antagonist (IC50 = 1.3 nM). Displays antihypertensive activity. Orally bioavailable.

Product Specifications for Irbesartan

Molecular Weight

428.53

Formula

C25H28N6O

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2-Butyl-3-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one

CAS Number

138402-11-6

PubChem ID

3749

InChI Key

YOSHYTLCDANDAN-UHFFFAOYSA-N

SMILES

O=C(C1(CCCC1)N=C2CCCC)N2CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 42.85 100
Ethanol 4.29 10

Preparing Stock Solutions for Irbesartan

The following data is based on the product molecular weight 428.53.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.33 mL 11.67 mL 23.34 mL
5 mM 0.47 mL 2.33 mL 4.67 mL
10 mM 0.23 mL 1.17 mL 2.33 mL
50 mM 0.05 mL 0.23 mL 0.47 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Irbesartan

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Irbesartan

For research use only

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