Ischemin sodium salt

Tocris Bioscience | Catalog # 4695

CBP inhibitor; cell permeable
Tocris Bioscience
Discontinued Product
4695 has been discontinued. View all Bromodomain Inhibitors products.

Key Product Details

Description

CBP inhibitor; cell permeable
View all Bromodomain Inhibitors »

Product Description

Ischemin sodium salt is a CBP bromodomain inhibitor. Inhibits p53 interaction with CBP and decreases p53 transcriptional activity. Protects against Doxorubicin-induced apoptosis in cardiomyocytes in vitro. Cell permeable.

Product Specifications for Ischemin sodium salt

Molecular Weight

357.36

Formula

C15H16N3O4SNa

Storage

Store at +4°C

Purity

≥99% (HPLC)

Chemical Name

5-[(1E)-2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-2,4-dimethylbenzenesulfonic acid sodium salt

PubChem ID

64983

InChI Key

XWNMORIHKRROGW-UHFFFAOYSA-N

SMILES

CC1=CC(/N=N/C2=C(C)C=C(C)C(S(=O)(O[Na])=O)=C2)=C(N)C=C1O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 35.74 100
DMSO 35.74 100

Preparing Stock Solutions for Ischemin sodium salt

The following data is based on the product molecular weight 357.36.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.80 mL 13.99 mL 27.98 mL
5 mM 0.56 mL 2.80 mL 5.60 mL
10 mM 0.28 mL 1.40 mL 2.80 mL
50 mM 0.06 mL 0.28 mL 0.56 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 16 publications citing the usage of this product.

Product Documents for Ischemin sodium salt

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ischemin sodium salt

For research use only

Citations for Ischemin sodium salt

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